[ BIOINTEGRATION ]

N2 Biomedical continues to advance nanoscale coating technologies that enhance biocompatibility and promote tissue integration for medical implants. Our proprietary low temperature processes create nanoscale surface textures that promote biointegration while discouraging biofilm formation.

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NanoTitanium Coatings

Titanium and titanium oxide coatings are deposited as highly adherent thin films at a low temperature using our ion beam assisted deposition (IBAD) process. These nanostructured coatings significantly improve the biocompatibility and functionality of orthopedic implants and are particularly useful for PEEK components. These nanostructured films have been engineered to encourage osteoblast differentiation and proliferation while preventing bacterial attachment and biofilm formation.

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APPLICATIONS

  • Spinal interbodies
  • Dental implants
  • PEEK screws
  • Small joints
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BENEFITS

  • Improves biocompatibility of substrate material
  • Increases surface area
  • Creates beneficial surface textures
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SUBSTRATES

  • PEEK
  • Stainless steel
  • Cobalt-chromium
  • Titanium
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Mesoporous TiO2

The patented Mesoporous TiO2 is a proprietary system developed at N2 Biomedical to enhance the osseo-integrative properties of Titanium-coated PEEK implants by creating a porous TiO2 surface layer with features in the 1 to 50 nm range. The very large surface area of the mesoporous structure can result in preferential osteoblast differentiation.

Substrates Commonly Treated with Ion Implantation and Ion Beam Assisted Deposition

Co-Cr

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Improved surface
hardness

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Reduced
Friction

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Reduced
Corrosion

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Improved
Wettability

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Reduced
Biofilm

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Improved
Antimicrobial

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Improved
Biocompatibility

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Improved
Aesthetics

Titanium
Stainless
PEEK
Silicone
Polyurethane